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濡傛灉鍦ㄦ韩搴﹀拰涓昏棩鍚噺闁撴矑鏈夋壘鍒扮浉鎳�(y墨ng)鐨勬暩(sh霉)瀛�(xu茅)闂�(gu膩n)绯�锛屾垨鑰呰棩鍝佹€ц唱(zh矛)鐨勬敼璁婃湁鏅�(sh铆)闁撲緷璩存€�锛屽墖鍙兘灏�(du矛)绌�(w臎n)瀹氭€ц│椹�(y脿n)鏁�(sh霉)鎿�(j霉)閫�(j矛n)琛屽洖姝稿垎鏋愮⒑瀹氱敘(ch菐n)鍝佺殑鏈夋晥鏈燂紝鑰屼笉鑳芥帹绠楄棩鍝佺殑鏈夋晥鏈�銆傛鏅�(sh铆)锛岄暦(zh菐ng)鏈熺暀妯ｈ│椹�(y脿n)鐨勬檪(sh铆)闁撳拰绲�(ji茅)鏋滃氨鏄焙瀹氱敘(ch菐n)鍝佹湁鏁堟湡鐨勪緷鎿�(j霉)銆�
5銆佸井鐢熺墿鎬ц唱(zh矛)璁婂寲鐨勫垽鏂�
灏�(du矛)闈炵劇鑿屽埗鍔�锛屾噳(y墨ng)灏�(du矛)鍏朵腑鐨勫井鐢熺墿閫�(j矛n)琛屾帶鍒�銆傚皪(du矛)铏曟柟涓笉鍚槻鑵愬姂鐨勭敘(ch菐n)鍝侊紝鍒ゆ柗寰敓鐗╂€ц唱(zh矛)鏄惁鐧�(f膩)鐢熻畩鍖栦富瑕佷緷鎿�(j霉)钘ュ吀閫氬墖鐨勭浉闂�(gu膩n)瑕�(gu墨)瀹�銆傚皪(du矛)铏曟柟涓惈鏈夐槻鑵愬姂鐨勭敘(ch菐n)鍝�锛屽墖鎳�(y墨ng)鎺у埗闃茶厫鍔戠殑鍚噺锛岀⒑淇濆叾鍦ㄧ敘(ch菐n)鍝佹湁鏁堟湡鍏�(n猫i)閮借兘鐧�(f膩)鎻綔鐢�;闃茶厫鍔戠殑鍚噺璁婂寲涓嶅彈妯�(bi膩o)绀洪噺90%鐨勯檺鍒躲€傚皪(du矛)鐒¤弻鍒跺姂锛屾噳(y墨ng)閫�(j矛n)琛屽鍣ㄥ瘑灏佹€ф寫鎴�(zh脿n)瑭﹂(y脿n)锛屼互纰轰繚鐢�(ch菐n)鍝佸湪鏈夋晥鏈熷収(n猫i)閬�(d谩)鍒扮劇鑿岃姹傘€備絾鏄�锛屽井鐢熺墿鎬ц唱(zh矛)涓嶈兘寰�1锝�2鎵规ǎ鍝佺殑鐮旂┒绲�(ji茅)鏋滈€�(j矛n)琛屽鎺�锛屽洜?y脿n)妲测懜顚濋攺鎸犵粖鎳歌洨鐫捐姀鍟靛枬缂侀挌鐚跨厼甯р懁o鏂�銆佺敓鐢�(ch菐n)鐠�(hu谩n)澧冨拰鍖呰绛夊潎鍙奖闊跨敘(ch菐n)鍝佺殑寰敓鐗╂€ц唱(zh矛)锛岄€欎竴榛�(di菐n)鎳�(y墨ng)鐗瑰垾娉ㄦ剰銆�
6銆佺⒑瀹氳棩鍝佹湁鏁堟湡鏅�(sh铆)闇€娉ㄦ剰鐨勫晱椤�
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a.鏈夋晥鏈熼仼鐢ㄤ簬瑭茬敘(ch菐n)鍝�锛屽洜姝わ紝鍍呬緷鎿�(j霉)涓€鎵圭敘(ch菐n)鍝佺殑绌�(w臎n)瀹氭€у氨鍋氬嚭绲�(ji茅)璜栨槸涓嶅鐨�锛岃嚦灏戞噳(y墨ng)灏�(du矛)涓夋壒鐢�(ch菐n)鍝佺殑绌�(w臎n)瀹氭€ч€�(j矛n)琛岀爺绌讹紝鑰屼笖鍖呮嫭涓嶅悓瑕�(gu墨)妯℃ǎ鍝佺殑绌�(w臎n)瀹氭€ц│椹�(y脿n)鏁�(sh霉)鎿�(j霉)銆�
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b.鍦ㄩ€�(j矛n)琛岀┅(w臎n)瀹氭€ц│椹�(y脿n)鏁�(sh霉)鎿�(j霉)鍒嗘瀽鏅�(sh铆)锛屾噳(y墨ng)灏�(du矛)鎵€鏈夊彲浠ュ畾閲忕殑璩�(zh矛)閲忔寚妯�(bi膩o)閫�(j矛n)琛屾柟宸垎鏋�锛屼互纰哄畾涓嶅悓鎵规妯ｅ搧涔嬮枔鏄惁瀛樺湪绲�(t菕ng)瑷�(j矛)瀛�(xu茅)宸暟锛屽鏋滄矑鏈夌当(t菕ng)瑷�(j矛)瀛�(xu茅)宸暟锛屽墖鍙互寰楀嚭鐩告噳(y墨ng)鐨勭祼(ji茅)璜栥€傚皪(du矛)灏忚│銆佷腑瑭﹀拰澶х敓鐢�(ch菐n)妯ｅ搧绌�(w臎n)瀹氭€ф暩(sh霉)鎿�(j霉)閫�(j矛n)琛屾柟宸垎鏋愬挨鐐洪噸瑕侊紝濡傛灉涓嶅悓瑕�(gu墨)妯℃ǎ鍝佺殑绌�(w臎n)瀹氭€ц│椹�(y脿n)鏁�(sh霉)鎿�(j霉)娌掓湁绲�(t菕ng)瑷�(j矛)瀛�(xu茅)宸暟锛屽墖鍙互瑾�(r猫n)鐐哄皣渚嗙敓鐢�(ch菐n)鏅�(sh铆)涓嶅悓鎵规鐢�(ch菐n)鍝佺殑绌�(w臎n)瀹氭€ф矑鏈夊樊鐣�锛屽洜?y脿n)姗勫棨顑�?gu墨)妯＄敘(ch菐n)鍝佺殑璩�(zh矛)閲忓樊鐣颁笉鏈�(hu矛)澶т簬涓嶅悓瑕�(gu墨)妯＄敘(ch菐n)鍝佺殑璩�(zh矛)閲忓樊鐣�銆�
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c.鐢�(ch菐n)鍝佺┅(w臎n)瀹氭€х殑閲嶈淇℃伅涓昏渚嗚嚜纰哄畾铏曟柟妯ｅ搧鐨勫姞閫熻│椹�(y脿n)锛屾牴鎿�(j霉)鍙嶆噳(y墨ng)鍕�(d貌ng)鍔涘(xu茅)瑕佹眰瑷�(sh猫)瑷�(j矛)鍔犻€熻│椹�(y脿n)锛�3鍊�(g猫)鏈堝氨鍩烘湰鍙互闋�(y霉)鐭ョ敘(ch菐n)鍝佺殑鏈夋晥鏈�銆傛牴鎿�(j霉)闀�(zh菐ng)鏈熺暀妯ｈ│椹�(y脿n)鏁�(sh霉)鎿�(j霉)闋�(y霉)娓�(c猫)鐢�(ch菐n)鍝佹湁鏁堟湡鏅�(sh铆)闇€鑸囧姞閫熻│椹�(y脿n)鎺ㄧ畻鐨勭祼(ji茅)鏋滈€�(j矛n)琛屾瘮杓�锛屽鏋�6鍊�(g猫)鏈堝悗闀�(zh菐ng)鏈熻│椹�(y脿n)绲�(ji茅)鏋滆垏鍙嶆噳(y墨ng)鍕�(d貌ng)鍔涘(xu茅)瑷�(j矛)绠楃殑涓昏棩鍚噺璁婂寲涓€鑷�锛屽墖闇€绻肩簩(x霉)鑰冨療鍏╃ó鏂规硶鐨勭祼(ji茅)鏋滆兘鍚﹀湪鐢�(ch菐n)鍝佺殑鏁村€�(g猫)鏈夋晥鏈熷収(n猫i)涓€鑷�銆�
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d.鍥犱笉鍚屽湅(gu贸)瀹跺拰鍦板崁(q奴)鐨勬埃鍊欐浠朵笉鍚�锛岄暦(zh菐ng)鏈熺暀妯ｈ│椹�(y脿n)姊濅欢鐨勮ō(sh猫)瀹氫富瑕佷緷鎿�(j霉)钘ュ搧娉ㄥ唺(c猫)鍦�(gu贸)瀹舵垨鍦板崁(q奴)鐨勬埃鍊欐浠�锛岃嫢钘ュ搧鍦ㄥ叏鐞冧笂甯傛垨鑰呴姺鍞殑鍦板煙姘ｅ€欏樊鍒ヨ純澶э紝鍏剁┅(w臎n)瀹氭€ц│椹�(y脿n)鎳�(y墨ng)鍦ㄧ洝鍙兘澶氱殑鍦�(gu贸)瀹跺拰鍦板崁(q奴)閫�(j矛n)琛�銆傚洜?y脿n)闂囧洘缇よ湊绌搁箠娣栧厯鐦滎暫?hu矛)褰遍熆钘ュ搧鐨勬湁鏁堟湡锛屾湁瑭﹂(y脿n)椤ず婧害鍗囬珮2鈩�锛岀敘(ch菐n)鍝佺殑鏈夋晥鏈熷皣鏈�(hu矛)绺煭20%銆�
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e.姣忓€�(g猫)姘ｅ€欏崁(q奴)鐢�(ch菐n)鍝佺殑鏈夋晥鏈熸槸鏍规摎(j霉)鐩告噳(y墨ng)鐨勭┅(w臎n)瀹氭€ц│椹�(y脿n)绲�(ji茅)鏋滅⒑瀹氱殑銆傞洊鐒舵瘡鍊�(g猫)姘ｅ€欏崁(q奴)鐨勫钩鍧囩啽鍔涘(xu茅)婧害鍦ㄨō(sh猫)瀹氭檪(sh铆)宸茬稉(j墨ng)灏囪┎姘ｅ€欏崁(q奴)涓€骞翠腑鍙兘瀛樺湪鐨勬韩搴︽尝鍕�(d貌ng)鑰冩叜鍦ㄥ収(n猫i)锛屼絾鍥犱竴浜涚敘(ch菐n)鍝佸皪(du矛)鐭檪(sh铆)闁撳収(n猫i)杓冮珮鐨勬韩搴︽晱鎰�锛屽洜姝ゅ皪(du矛)閫欓鐢�(ch菐n)鍝佽姹傛槑纰哄瓨鍎�(ch菙)婧害鐨勪笂闄�銆�
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涓嬮潰鏄編鍦�(gu贸)FDA闋掑竷鐨勬(bi膩o)婧�(zh菙n)锛屽彲鍦ㄧ⒑瀹氳棩鍝佹湁鏁堟湡璨棌姊濅欢鏅�(sh铆)鍙冭€冿細蹇呴爤鍦�+25鈩冧互涓嬩繚瀛�;蹇呴爤鍦�+20鈩冧互涓嬩繚瀛�;蹇呴爤鍦�+8鈩冧互涓嬩繚瀛�;蹇呴爤鍦�+8鈩冧互涓婁繚瀛�;蹇呴爤鍦ㄥ共鐕ヨ檿淇濆瓨;蹇呴爤閬垮厜淇濆瓨銆傜壒娈婃儏娉佷笅涔熸渻(hu矛)浣跨敤浠ヤ笅妯�(bi膩o)婧�(zh菙n)锛氬繀闋堝湪+30鈩冧互涓嬩繚瀛�;蹇呴爤鍦�+15鈩冧互涓嬩繚瀛樸€�
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f.鍦ㄦ敼璁婅檿鏂瑰拰鐢熺敘(ch菐n)宸ヨ棟鏅�(sh铆)锛屽父甯哥劇娉曠嵅寰�2锝�3鎵规ǎ鍝佺殑绌�(w臎n)瀹氭€ц│椹�(y脿n)鏁�(sh霉)鎿�(j霉)锛屾鏅�(sh铆)鐮旂┒鑰呮噳(y墨ng)瑷�(sh猫)娉曡瓑鏄庤檿鏂瑰伐钘濇敼璁婂墠鍚庣敘(ch菐n)鍝佺殑绌�(w臎n)瀹氭€ф矑鏈夊樊鐣帮紝鍓囧彲浠ュ€熼憭铏曟柟宸ヨ棟鏀硅畩鍓嶇殑绌�(w臎n)瀹氭€ц│椹�(y脿n)鏁�(sh霉)鎿�(j霉)銆傚鏋滆檿鏂瑰伐钘濈殑鏀硅畩鍙兘鏈�(hu矛)灏�(du矛)鐢�(ch菐n)鍝佺殑鏈夋晥鏈熺敘(ch菐n)鐢熷奖闊�锛屽墖鎳�(y墨ng)灏�(du矛)澶氭壒妯ｅ搧閫�(j矛n)琛岀┅(w臎n)瀹氭€х爺绌�锛岀嵅鍙栬純瀹屾暣鐨勭┅(w臎n)瀹氭€т俊鎭�锛屼互鎺ㄧ畻鐢�(ch菐n)鍝佺殑鏈夋晥鏈熴€�
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